Menke-Hennekam syndrome
ORPHA: 592574
Overview
medical condition
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Menke-Hennekam syndrome, sourced from HPO and Orphanet clinical annotations.
Intellectual disabilityFeeding difficulties in infancyCryptorchidismAbnormality of the dentitionMicrocephalyEpicanthusAbnormality of the philtrumHypertelorismHearing impairmentLow-set earsAnteverted naresStrabismusTelecanthusPtosisLong eyelashesHypermetropiaAutistic behaviorMotor delayIntrauterine growth retardationSandal gapShort columellaHighly arched eyebrowRecurrent upper respiratory tract infectionsShort noseDepressed nasal bridgeProminent foreheadSlanting of the palpebral fissureInguinal herniaCleft palateMyopiaSeizureHip dysplasiaSmall for gestational ageUmbilical herniaAbnormal heart morphologyScoliosisClinodactyly of the 5th fingerShort statureAbnormality of the upper urinary tractCutaneous syndactylyOverweightAbnormality of thyroid physiologyCerebral white matter atrophyReduced circulating growth hormone concentration
Classification & Codes
Orphanet Code
ORPHA:592574Menke-Hennekam syndrome
| Orphanet | ORPHA:592574 |
| Treatments | 0 drug(s) |
| Symptoms on record | 44 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO