microcephaly lymphoedema chorioretinal dysplasia

MeSH: C537711ORPHA: 2526

Overview

syndrome characterized byvariable expression of microcephaly, ocular disorders including chorioretinopathy, congenital lymphedema of the lower limbs, and mild to moderate intellectual disability

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with microcephaly lymphoedema chorioretinal dysplasia, sourced from HPO and Orphanet clinical annotations.

Chorioretinal dysplasiaRetinal dysplasiaUnderdeveloped supraorbital ridgesChylothoraxThick vermilion borderPanniculitisScaling skinCellulitisGangreneSkin ulcerMicrocephalyAbnormality of the eyeAbnormality of visionLymphedemaMyopiaEdemaIntellectual disabilityHypotoniaGlobal developmental delaySpecific learning disabilityAbnormal hair morphologyLeukonychiaAbnormal retinal pigmentationAbnormal toenail morphologyMelanonychiaEpicanthusFull cheeksPointed chinSloping foreheadLong philtrumProtruding earWide nasal bridgeWide noseAnteverted naresRetinopathyAbnormal eyelid morphologyAbnormal eyelash morphologyGlaucomaPtosisCataractAnophthalmiaRetinal detachmentRetinal dystrophyMicrophthalmiaVisual lossUpslanted palpebral fissureAbnormal optic nerve morphologyAbnormal nasolacrimal system morphologyBlindnessAmblyopiaOptic atrophyDry skinErysipelasThickened skinSeizureSpasticityHypertoniaSubcutaneous noduleAtrial septal defectLeukemiaRigidityStatus epilepticusPleural effusionLymphomaSevere short statureMuscle stiffnessVenous thrombosis

Classification & Codes

MeSH Code

C537711

Orphanet Code

ORPHA:2526
microcephaly lymphoedema chorioretinal dysplasia
MeSHC537711
OrphanetORPHA:2526
Treatments0 drug(s)
Symptoms on record67 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
microcephaly lymphoedema chorioretinal dysplasia | OrphanDrug