Mikulicz disease
MeSH: D008882ORPHA: 79078
Overview
Human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Mikulicz disease, sourced from HPO and Orphanet clinical annotations.
Enlarged lacrimal glandsAbnormal salivary gland morphologyAbnormality of the submandibular glandsIncreased circulating IgG4 levelEnlargement of parotid glandXerostomiaFacial edemaAbnormality of the orbital regionProptosisAbnormal optic nerve morphologyPeriorbital fullnessKeratoconjunctivitis siccaWeight lossFeverAutoimmunityIncreased circulating IgA concentrationGeneralized muscle weaknessAntinuclear antibody positivityIncreased circulating IgM levelAbnormality of the extraocular musclesFatigueCytoplasmic antineutrophil antibody positivityPalpebral edemaMyositisBlindnessThrombocytopeniaTubulointerstitial nephritisLymphadenopathyRetroperitoneal fibrosisNodular goiterOptic nerve compressionAbnormal lacrimal duct morphologyThyroiditis
Classification & Codes
MeSH Code
D008882Orphanet Code
ORPHA:79078Mikulicz disease
| MeSH | D008882 |
| Orphanet | ORPHA:79078 |
| Treatments | 0 drug(s) |
| Symptoms on record | 33 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO