Miller Fisher syndrome

MeSH: D019846ORPHA: 98919

Overview

Guillain-Barre syndrome that manifests as a descending paralysis

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Miller Fisher syndrome, sourced from HPO and Orphanet clinical annotations.

External ophthalmoplegiaAreflexiaAnti-GQ1b antibody positivityDiplopiaHorizontal nystagmusAtaxiaIncreased CSF protein concentrationEMG abnormalityInternal ophthalmoplegiaEEG with generalized slow activityMydriasisPhotophobiaBlurred visionBulbar palsyFeverTetraparesisHeadacheParesthesiaReduced consciousnessAnisocoriaFacial palsyAbnormality of ocular abductionCSF pleocytosisPtosisVomitingDysphagia

Classification & Codes

MeSH Code

D019846

Orphanet Code

ORPHA:98919
Miller Fisher syndrome
MeSHD019846
OrphanetORPHA:98919
Treatments0 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO