mitochondrial DNA deletion syndrome with progressive myopathy

ORPHA: 352470

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with mitochondrial DNA deletion syndrome with progressive myopathy, sourced from HPO and Orphanet clinical annotations.

MyopathyHyperlordosisMyalgiaGowers signMuscle spasmMitochondrial myopathyDecreased facial expressionCongenital ptosisElevated creatine kinase after exerciseDecreased mitochondrial numberProgressive external ophthalmoplegiaLimb-girdle muscle weaknessDepressionGait disturbanceGeneralized hypotoniaSlender buildDecreased fetal movementMultiple joint contracturesObstructive sleep apneaExertional dyspnea

Classification & Codes

Orphanet Code

ORPHA:352470
mitochondrial DNA deletion syndrome with progressive myopathy
OrphanetORPHA:352470
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO