Mobius syndrome
MeSH: D020331ORPHA: 570
Overview
rare disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Mobius syndrome, sourced from HPO and Orphanet clinical annotations.
Open mouthMask-like faciesStrabismusPtosisOphthalmoplegiaAbnormality of the voiceCranial nerve paralysisFeeding difficulties in infancyFacial palsyEverted lower lip vermilionBrachydactylyHypotoniaMotor delayTalipes equinovarusDysphagiaCorneal opacityAplasia of the pectoralis major muscleHypogonadotropic hypogonadismCleft palateHigh palateEpicanthusMicrognathiaHearing impairmentBlepharitisVisual impairmentMicrodontiaAutismArthrogryposis multiplex congenitaSkeletal muscle atrophyAbsent handClinodactyly of the 5th fingerAbnormality of the sense of smellAplasia/Hypoplasia involving the metacarpal bonesFinger syndactylyAplasia/Hypoplasia of the radiusMultiple cafe-au-lait spotsAplasia/Hypoplasia of the thumbTooth agenesisAplasia/Hypoplasia of the tongueAbnormal morphology of ulnaBreast aplasia
Classification & Codes
MeSH Code
D020331Orphanet Code
ORPHA:570Mobius syndrome
| MeSH | D020331 |
| Orphanet | ORPHA:570 |
| Treatments | 0 drug(s) |
| Symptoms on record | 41 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO