moderately severe hemophilia A

ORPHA: 169805

Overview

Moderately severe hemophilia A is a form of hemophilia A (see this term) characterized by factor VIII deficiency leading to abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with moderately severe hemophilia A, sourced from HPO and Orphanet clinical annotations.

Intraventricular hemorrhageEpidural hemorrhageAbnormal bleedingReduced factor VIII activityProlonged partial thromboplastin timeGingival bleedingSubcutaneous hemorrhageArthralgiaJoint hemorrhageBleeding with minor or no traumaIntramuscular hematomaHematuriaLimitation of joint mobilityJoint swellingIntracranial hemorrhageGastrointestinal hemorrhageHeadacheArthropathyProlonged bleeding after surgeryProlonged bleeding after dental extractionSubdural hemorrhageSynovitisCartilage destructionSeizureHip contractureSpontaneous hematomas

Classification & Codes

Orphanet Code

ORPHA:169805
moderately severe hemophilia A
OrphanetORPHA:169805
Treatments0 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO