Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome

MeSH: C535806ORPHA: 2560

Overview

This syndrome is characterized by the association of MC6bius syndrome (congenital facial palsy with impaired ocular abduction; see this term) with peripheral axonal neuropathy and hypogonadotropic hypogonadism

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome, sourced from HPO and Orphanet clinical annotations.

Hypogonadotropic hypogonadismMovement abnormality of the tongueMask-like faciesStrabismusExternal ophthalmoplegiaAbnormal finger morphologyHypotoniaBilateral talipes equinovarusModerate intellectual disabilityInability to walkPeripheral axonal neuropathyDemyelinating peripheral neuropathyFacial paralysisDecreased corneal reflexAbnormality of jaw muscles

Classification & Codes

MeSH Code

C535806

Orphanet Code

ORPHA:2560
Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome
MeSHC535806
OrphanetORPHA:2560
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO