molybdenum cofactor deficiency

ORPHA: 997321 Treatment Available

Overview

metal metabolism disease characterized by encephalopathy that worsens over time resulting from the absence of molybdenum cofactor which leads to accumulation of toxic levels of sulphite and neurological damage

Available Treatments (1)

DrugFormStatusCountriesLead Time
fosdenopterin
Orphan Cold Chain
Intravenous infusion, 0.44mg/mL concentrate for solutionFDA Approved (2021), Unregistered in India330d

Classification & Codes

Orphanet Code

ORPHA:99732
molybdenum cofactor deficiency
OrphanetORPHA:99732
Treatments1 drug(s)
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO