mu chain disease

ORPHA: 100024

Overview

heavy chain disease that results from an overproduction of mu antibody (IgM)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with mu chain disease, sourced from HPO and Orphanet clinical annotations.

NephropathyOsteoporosisSplenomegalyWeight lossAnemiaFeverHepatomegalyLymphadenopathyOsteolysisAbnormal bone marrow cell morphologyIncreased circulating immunoglobulin concentrationAbnormal B cell countBence Jones Proteinuria

Classification & Codes

Orphanet Code

ORPHA:100024
mu chain disease
OrphanetORPHA:100024
Treatments0 drug(s)
Symptoms on record13 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO