Muckle-Wells syndrome
ICD-10: E85.0ORPHA: 85450
Overview
Human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Muckle-Wells syndrome, sourced from HPO and Orphanet clinical annotations.
ProteinuriaNephropathyRenal interstitial amyloid depositsRenal insufficiencyHypertensionTubulointerstitial nephritisElevated circulating creatinine concentrationAbnormality of the gastrointestinal tractDecreased glomerular filtration rateAbnormal urinary electrolyte concentrationNocturiaRenal tubular atrophyNephrotic syndromePetechiaePurpuraDecreased liver functionHepatosplenomegalyCongestive heart failureWeight lossAnemiaVomitingDiarrheaNauseaGastroesophageal refluxAbdominal painGastrointestinal hemorrhageHepatomegalyLymphadenopathyAbnormal lymph node morphologyMyopathyDecreased HDL cholesterol concentrationElevated erythrocyte sedimentation rateIntestinal obstructionTubulointerstitial fibrosisPeripheral neuropathyIntestinal perforationDecreased circulating apolipoprotein A-I concentrationDyspepsiaAbnormal testis morphologyHypogonadismOligozoospermiaMale infertilityPrimary testicular failure
Classification & Codes
ICD-10 Code
E85.0Orphanet Code
ORPHA:85450Muckle-Wells syndrome
| ICD-10 | E85.0 |
| Orphanet | ORPHA:85450 |
| Treatments | 0 drug(s) |
| Symptoms on record | 43 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO