mucolipidosis type III

ORPHA: 577

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with mucolipidosis type III, sourced from HPO and Orphanet clinical annotations.

Genu valgumHyperlordosisCorneal opacityProminent occiputVisual impairmentJoint stiffnessDeficiency of N-acetylglucosamine-1-phosphotransferaseAbnormal hip bone morphologyAbnormal form of the vertebral bodiesShort statureCraniofacial hyperostosisLarge iliac wingHypoplastic inferior iliaStiff fingerCoarse facial featuresOsteopeniaDysostosis multiplexHip dysplasiaMitral valve prolapseScoliosisOsteoarthritisBullet-shaped distal phalanges of the handConstrictive median neuropathyChronic painAbnormal cardiovascular system morphologyClaw hand deformityCognitive impairmentBroad ribsThickened skinMitral regurgitationAortic regurgitationRestrictive ventilatory defectSpinal cord compressionWaddling gaitReduced bone mineral densityFatigue

Classification & Codes

Orphanet Code

ORPHA:577
mucolipidosis type III
OrphanetORPHA:577
Treatments0 drug(s)
Symptoms on record36 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO