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Multifocal motor neuropathy

ICD-10: G61.8ORPHA: 641

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

Multifocal motor neuropathy (MMN) is a rare acquired immune-mediatedneuropathy characterized clinically by a purely motor deficit with conduction block and asymmetric multifocal weakness, fasciculations, and cramping

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Multifocal motor neuropathy, sourced from HPO and Orphanet clinical annotations.

Progressive distal muscle weaknessReduced tendon reflexesFasciculationsIncreased CSF protein concentrationProgressive muscle weaknessMuscle spasmLimb muscle weaknessFunctional motor deficitGanglioside accumulationLimited wrist extensionWeakness of long finger extensor musclesMotor conduction block

Classification & Codes

ICD-10 Code

G61.8

Orphanet Code

ORPHA:641
Multifocal motor neuropathy
ICD-10G61.8
OrphanetORPHA:641
Treatments0 drug(s)
Symptoms on record12 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO