multiple epiphyseal dysplasia due to collagen 9 anomaly

ORPHA: 166002

Overview

multiple epiphyseal dysplasia that has material basis in mutation in any of the members of the COL9A gene family (COL9A1, COL9A2, COL9A3)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with multiple epiphyseal dysplasia due to collagen 9 anomaly, sourced from HPO and Orphanet clinical annotations.

Abnormal epiphysis morphologyArthralgia of the hipLimb undergrowthReduced arm spanKnee painPostexertional symptom exacerbationWaddling gaitOsteoarthritisCoxa varaAbnormality of the kneeGenu valgumGenu varumAbnormality of the ankleAbnormal patella morphologyAbnormal elbow epiphysis morphologyAbnormal radial epiphysis morphologyShort statureUlnar deviated club handsRadially deviated wristsFragmented metacarpal epiphysisAbnormality of the epiphyses of the feetBilateral coxa valgaMuscle weaknessMyopathy

Classification & Codes

Orphanet Code

ORPHA:166002
multiple epiphyseal dysplasia due to collagen 9 anomaly
OrphanetORPHA:166002
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO