multiple system atrophy
ICD-10: G232MeSH: D019578ORPHA: 102
Overview
neurodegenerative disorder characterized by autonomic failure, parkinsonism, cerebellar impairment and corticospinal signs, with a median survival of 6-9 years
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with multiple system atrophy, sourced from HPO and Orphanet clinical annotations.
Gaze-evoked nystagmusDysarthriaParkinsonismConstipationRigidityGait ataxiaBradykinesiaProgressive cerebellar ataxiaPostural instabilityPostural tremorOrofacial dyskinesiaResting tremorFrequent fallsAbnormal rapid eye movement sleepAxial dystoniaOrthostatic hypotension due to autonomic dysfunctionAutonomic bladder dysfunctionAbnormal pyramidal signAutonomic erectile dysfunctionStridorCentral sleep apneaAbnormal brain FDG positron emission tomographyOrthostatic syncopeFemale anorgasmiaRaynaud phenomenonCamptocormiaAbnormal autonomic nervous system physiology
Classification & Codes
ICD-10 Code
G232MeSH Code
D019578Orphanet Code
ORPHA:102multiple system atrophy
| ICD-10 | G232 |
| MeSH | D019578 |
| Orphanet | ORPHA:102 |
| Treatments | 0 drug(s) |
| Symptoms on record | 27 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO