multiple system atrophy, cerebellar type

ORPHA: 227510

Overview

Multiple system atrophy, cerebellar type (MSA-c) is a form of multiple system atrophy (MSA; see this term) with predominant cerebellar features (gait and limb ataxia, oculomotor dysfunction, and dysarthria)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with multiple system atrophy, cerebellar type, sourced from HPO and Orphanet clinical annotations.

Gaze-evoked nystagmusDepressionAnxietyDysarthriaDysphoniaConstipationGait ataxiaNeuromuscular dysphagiaLimb ataxiaProgressive cerebellar ataxiaBroad-based gaitPostural instabilityPostural tremorOrofacial dyskinesiaFrequent fallsAbnormal rapid eye movement sleepAxial dystoniaOrthostatic hypotension due to autonomic dysfunctionAutonomic bladder dysfunctionAbnormal pyramidal signAutonomic erectile dysfunctionStridorCentral sleep apneaDownbeat nystagmusAbnormal autonomic nervous system physiologyAbnormal brain FDG positron emission tomographyOrthostatic syncopeFemale anorgasmiaRaynaud phenomenonApathyParkinsonismRigidityBradykinesiaResting tremorCamptocormia

Classification & Codes

Orphanet Code

ORPHA:227510
multiple system atrophy, cerebellar type
OrphanetORPHA:227510
Treatments0 drug(s)
Symptoms on record35 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO