nephrogenic diabetes insipidus-intracranial calcification syndrome

ICD-10: N25.1MeSH: C535949ORPHA: 3145

Overview

This syndrome is characterised by nephrogenic diabetes insipidus, intracerebral calcifications, intellectual deficit, short stature and facial dysmorphism

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with nephrogenic diabetes insipidus-intracranial calcification syndrome, sourced from HPO and Orphanet clinical annotations.

MicrognathiaConductive hearing impairmentDownslanted palpebral fissuresCarious teethDelayed pubertyIntellectual disabilityGlobal developmental delayLimitation of joint mobilityAbnormality of metabolism/homeostasisCerebral calcificationShort statureAbnormal antihelix morphologyNephrogenic diabetes insipidusHypoplasia of the zygomatic boneSupernumerary toothPolyuriaPolydipsiaNocturiaHyposthenuria

Classification & Codes

ICD-10 Code

N25.1

MeSH Code

C535949

Orphanet Code

ORPHA:3145
nephrogenic diabetes insipidus-intracranial calcification syndrome
ICD-10N25.1
MeSHC535949
OrphanetORPHA:3145
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO