Neu-Laxova syndrome

MeSH: C536405ORPHA: 2671

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Neu-Laxova syndrome, sourced from HPO and Orphanet clinical annotations.

PachygyriaMicrocephalySloping foreheadIntrauterine growth retardationIchthyosisThick vermilion borderAbnormal nervous system morphologyLack of skin elasticityAmbiguous genitaliaHypogonadismAbnormality of the mouthTrismusEverted lower lip vermilionAbnormality of the philtrumHypertelorismMacrotiaDepressed nasal ridgeProptosisAbnormality of the skinLarge handsDandy-Walker malformationCerebellar hypoplasiaAbsent septum pellucidumLissencephalyFlexion contractureAplasia/Hypoplasia involving the skeletal musculatureDecreased fetal movementPolyhydramniosBroad footPolymicrogyriaOpisthotonusAbnormality of neuronal migrationAbnormal cerebellar vermis morphologyAbnormal cortical gyrationSkeletal muscle atrophyExternal genital hypoplasiaMuscle spasmMuscular dystrophyCleft palateSubmucous cleft hard palateBifid uvulaProminent occiputRetrognathiaMicrognathiaAbnormal eyelid morphologyAbnormal eyelash morphologyCataractAbnormal nasolacrimal system morphologyOsteopeniaOsteoporosisPterygiumAbnormal hair morphologyPulmonary hypoplasiaVentriculomegalySpina bifidaCerebral calcificationScoliosisRicketsOsteomalaciaArthrogryposis multiplex congenitaMicromeliaAbnormal cardiovascular system morphology

Classification & Codes

MeSH Code

C536405

Orphanet Code

ORPHA:2671
Neu-Laxova syndrome
MeSHC536405
OrphanetORPHA:2671
Treatments0 drug(s)
Symptoms on record62 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO