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neurogenic arthrogryposis multiplex congenita

MeSH: C536614ORPHA: 1143

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

congenital joint contracture in two or more areas of the body

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with neurogenic arthrogryposis multiplex congenita, sourced from HPO and Orphanet clinical annotations.

Flexion contractureEMG: chronic denervation signsWrist flexion contractureAreflexiaElbow flexion contractureSkeletal muscle atrophyUpper limb muscle weaknessKnee flexion contractureAnkle flexion contractureLower limb muscle weaknessMildly elevated creatine kinaseHypertelorismMicrognathiaPlagiocephalyDecreased fetal movementOligohydramniosBreech presentationAbnormal heart morphologyRocker bottom footMyopathic faciesRespiratory distressFasciculationsScoliosisRespiratory insufficiency due to muscle weaknessHip dislocationHip contractureAbnormal dermatoglyphicsEquinovarus deformityAcetabular dysplasiaSkin dimpleFeeding difficultiesScaphocephalyBrain imaging abnormality

Classification & Codes

MeSH Code

C536614

Orphanet Code

ORPHA:1143
neurogenic arthrogryposis multiplex congenita
MeSHC536614
OrphanetORPHA:1143
Treatments0 drug(s)
Symptoms on record33 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO