Neuromyelitis Optica Spectrum Disorder

Overview

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disorder of the central nervous system primarily affecting the optic nerves and spinal cord. Approximately 80% of patients have aquaporin-4 antibodies (AQP4-IgG). Clinical features include severe optic neuritis, longitudinally extensive transverse myelitis, and area postrema syndrome. Prevalence varies by ethnicity, ranging from 0.5 to 10 per 100,000, with higher rates in Asian and African populations.

Available Treatments (0)

Classification & Codes