Nezelof syndrome
MeSH: C536288ORPHA: 83471
Overview
Human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Nezelof syndrome, sourced from HPO and Orphanet clinical annotations.
Eczematoid dermatitisAplasia of the thymusRecurrent infectionsSevere T-cell immunodeficiencyCellular immunodeficiencyDecreased total T cell countDecreased mitogen-induced T-cell proliferationDecreased naive T cell proportionFailure to thrivePneumoniaRecurrent bacterial infectionsAutoimmunityRecurrent infection of the gastrointestinal tractOpportunistic infectionSevere viral infectionSevere infectionRecurrent urinary tract infectionsSinusitisChronic otitis mediaHypothyroidismMeningitisDiarrheaMalabsorptionLymphadenopathyRecurrent Staphylococcus aureus infectionsHypocalcemic tetanyCoombs-positive hemolytic anemiaRecurrent streptococcus pneumoniae infectionsCombined immunodeficiencyRecurrent candida infectionsChronic oral candidiasisInvasive fungal infectionOligoclonal T cell expansionThyroiditisSepsisAtypical or prolonged hepatitis
Classification & Codes
MeSH Code
C536288Orphanet Code
ORPHA:83471Nezelof syndrome
| MeSH | C536288 |
| Orphanet | ORPHA:83471 |
| Treatments | 0 drug(s) |
| Symptoms on record | 36 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO