Nicolaides–Baraitser syndrome

MeSH: C536116ORPHA: 3051

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Nicolaides–Baraitser syndrome, sourced from HPO and Orphanet clinical annotations.

Wide mouthEverted lower lip vermilionThin vermilion borderMicrocephalySmooth philtrumTriangular faceLong philtrumAnteverted naresBrachydactylyIntellectual disabilityGlobal developmental delaySpecific learning disabilityJoint dislocationAlopeciaMutismAphasiaHigh, narrow palateShort palmSparse hairThick nasal alaeEcholaliaCryptorchidismAbnormal testis morphologyNarrow nasal bridgeLong eyelashesBlepharophimosisEczematoid dermatitisAbnormal finger morphologySeizureSandal gapGeneralized non-motor (absence) seizureStatus epilepticusHighly arched eyebrowScoliosisSevere short statureWide intermamillary distanceExcessive wrinkled skinCurly eyelashesBroad distal phalanx of fingerAbnormal hair patternEpileptic spasmShort palpebral fissureClubbing of toesDownslanted palpebral fissuresDelayed skeletal maturationAccelerated skeletal maturationAbnormal epiphysis morphologyAbnormal cardiovascular system morphologyHerniaAbnormal metacarpal morphology

Classification & Codes

MeSH Code

C536116

Orphanet Code

ORPHA:3051
Nicolaides–Baraitser syndrome
MeSHC536116
OrphanetORPHA:3051
Treatments0 drug(s)
Symptoms on record50 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO