ocular paraneoplastic syndrome

MeSH: D059545ORPHA: 71505

Overview

ocular manifestation secondary to various neoplasms in which antibodies to antigens of the primary tumor cross-react with ocular antigens

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with ocular paraneoplastic syndrome, sourced from HPO and Orphanet clinical annotations.

Visual lossPhotophobiaMalignant genitourinary tract tumorReduced visual acuityAdult-onset night blindnessERG: Reduced dark-adapted b-wave amplitudeProgressive visual field defectsAutoimmune antibody positivitySmall cell lung carcinomaPhotopsiaFemale reproductive system neoplasmNeoplasm of the breastAnti-recoverin antibody positivityOptic disc pallorCentral scotomaRetinal atrophyConstriction of peripheral visual fieldHematological neoplasmDyschromatopsiaRetinal pigment epithelial atrophyGranular macular appearanceUterine neoplasmTesticular neoplasmHodgkin lymphomaParacentral scotomaFoveal hyporeflective spaces on macular OCTDiffuse cerebellar atrophyThymomaOptic atrophyVisual hallucinationNeoplasm of the pancreasColon cancerPancreatic adenocarcinomaVitritisCutaneous melanomaProstate cancer

Classification & Codes

MeSH Code

D059545

Orphanet Code

ORPHA:71505
ocular paraneoplastic syndrome
MeSHD059545
OrphanetORPHA:71505
Treatments0 drug(s)
Symptoms on record36 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO