oculocerebrorenal syndrome

MeSH: D009800ORPHA: 534

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with oculocerebrorenal syndrome, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilityPosteriorly rotated earsFeeding difficulties in infancyNeoplasm of the skinDecreased circulating vitamin D concentrationAbnormal circulating calcium-phosphate regulating hormone concentrationSelf-injurious behaviorBenign neoplasm of the central nervous systemInguinal herniaAzoospermiaNephrocalcinosisAbnormality of the dentitionNarrow palateOpen mouthThin upper lip vermilionGingivitisEverted lower lip vermilionMandibular prognathiaLong philtrumMicrognathiaChronic otitis mediaStrabismusMicrophthalmiaUpslanted palpebral fissureLacrimation abnormalityCarious teethDental crowdingTaurodontiaAbnormal dental enamel morphologyDelayed eruption of teethPeriodontitisAbnormal rib morphologyNephrolithiasisHematuriaDelayed pubertyIncreased circulating aldosterone concentrationDiabetes insipidusPlatyspondylyAbnormal metaphysis morphologyAtypical scarring of skinJoint stiffnessUmbilical herniaAnemiaDeep philtrumGastroesophageal refluxMalabsorptionRespiratory insufficiencyHypophosphatemiaIncreased circulating lactate concentrationRecurrent respiratory infectionsKyphosisHip dislocationGenu valgumPatellar dislocationHypercholesterolemiaFlat occiputMultiple renal cystsAbnormal epiphysis morphologyChorioretinal dysplasiaCorneal opacityTooth agenesisOligosacchariduriaOpen biteLentiglobusHypoammonemiaUrogenital fistulaOdontogenic neoplasmAtelectasisCheilitisSkin ulcerGeneralized hypopigmentationRenal insufficiencyAbnormal renal tubule morphologyProteinuriaCataractAbnormal pupil morphologyNystagmusAmblyopiaDepressionMotor stereotypyAnxietyIntellectual disabilityAreflexiaNeonatal hypotoniaAbnormality of the voiceDehydrationProximal renal tubular acidosisHypercalciuriaAphasiaHyponatremiaAminoaciduriaShort statureGlomerulopathyCryptorchidismLong faceFull cheeksProtruding earDeeply set eyeGlaucomaBuphthalmosCompulsive behaviorsHyperparathyroidismSeizureArthritisJoint swellingFailure to thriveThrombocytopeniaFrontal bossingConstipationVentriculomegalyClonusSparse scalp hairFine hairEEG abnormalityScoliosisOsteomalaciaRecurrent fracturesHypokalemiaAttention deficit hyperactivity disorder

Classification & Codes

MeSH Code

D009800

Orphanet Code

ORPHA:534
oculocerebrorenal syndrome
MeSHD009800
OrphanetORPHA:534
Treatments0 drug(s)
Symptoms on record119 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
oculocerebrorenal syndrome | OrphanDrug