Oculopharyngodistal myopathy

MeSH: C563508ORPHA: 98897

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Oculopharyngodistal myopathy, sourced from HPO and Orphanet clinical annotations.

Gait disturbanceAbnormality of facial musculatureProgressive external ophthalmoplegiaOphthalmoparesisWeight lossProgressive ptosisNasal dysarthriaWeakness of facial musculatureTongue muscle weaknessHigh palateVocal cord paresisMyopathic faciesRecurrent aspiration pneumoniaHigh, narrow palateRespiratory insufficiency due to muscle weaknessDistal upper limb amyotrophyBowing of the vocal cordsDistal lower limb amyotrophyDistal lower limb muscle weaknessProgressive distal muscle weaknessImpaired oropharyngeal swallow responseOral-pharyngeal dysphagiaAbnormal morphology of musculature of pharynxProgressive sensorineural hearing impairmentAreflexiaRestrictive ventilatory defectLoss of ambulationDistal upper limb muscle weaknessTibialis muscle weaknessFoot dorsiflexor weaknessProgressive proximal muscle weaknessFatigable weakness of bulbar musclesAbnormality of masseter muscleProximal upper limb muscle weaknessParaplegiaAbnormality of orbicularis oris muscle

Classification & Codes

MeSH Code

C563508

Orphanet Code

ORPHA:98897
Oculopharyngodistal myopathy
MeSHC563508
OrphanetORPHA:98897
Treatments0 drug(s)
Symptoms on record36 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO