Ogden syndrome

ORPHA: 276432

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

X-linked disease resulting from a deficiency in N-terminal acetyltransferase, extreme abrupt behavior, anger issues, characterized by postnatal growth failure with severe delays and dysmorphic features in boys

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Ogden syndrome, sourced from HPO and Orphanet clinical annotations.

Delayed cranial suture closureTorticollisExcessive daytime somnolenceGlobal developmental delayGeneralized hypotoniaCerebral atrophyFine hairScoliosisPostnatal growth retardationBroad halluxAplasia/Hypoplasia of the eyebrowInguinal herniaCryptorchidismCoarse facial featuresAbnormal forehead morphologyMicroretrognathiaNarrow foreheadLow-set earsMacrotiaUnderdeveloped nasal alaeDownslanted palpebral fissuresProptosisAtypical behaviorAutistic behaviorCutis laxaLethargyHypertoniaVentricular septal defectShort columellaFrontal bossingVentriculomegalyDelayed gross motor developmentShuffling gaitAbnormal head movementsHigh, narrow palatePulmonary artery stenosisEnlarged narisEverted upper lip vermilionArrhythmiaCapillary malformationCardiogenic shock

Classification & Codes

Orphanet Code

ORPHA:276432

Ogden syndrome

Orphanet	`ORPHA:276432`
Treatments	0 drug(s)
Symptoms on record	41 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO