oligomeganephronia
ORPHA: 2260
Overview
renal hypoplasia characterized by bilateral reduced kidney size with a marked decrease in the total number of nephrons
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with oligomeganephronia, sourced from HPO and Orphanet clinical annotations.
Renal insufficiencyProteinuriaElevated circulating creatinine concentrationDecreased numbers of nephronsDecreased glomerular filtration rateAbnormal nephron morphologyBilateral renal hypoplasiaGlomerulomegalyRenal tubular atrophySmall for gestational agePremature birthStage 5 chronic kidney diseaseAbnormal renal cortex morphologyAbnormal medullary pyramid morphologyDehydrationPolydipsiaUnilateral renal agenesisAbnormality of the faceMicrognathiaHearing impairmentOptic disc colobomaCongenital diaphragmatic herniaHypertensionSeizureSecundum atrial septal defectPulmonary hypoplasiaPulmonary venous occlusionBranchial cystNeurodevelopmental delayAbnormality of limbs
Classification & Codes
Orphanet Code
ORPHA:2260oligomeganephronia
| Orphanet | ORPHA:2260 |
| Treatments | 0 drug(s) |
| Symptoms on record | 30 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO