Omenn syndrome

ORPHA: 39041

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Omenn syndrome, sourced from HPO and Orphanet clinical annotations.

Nephrotic syndromeHypothyroidismAbnormal metaphysis morphologyDry skinEdemaPruritusErythrodermaThickened skinFailure to thriveAlopeciaSplenomegalyShort toeIncreased total eosinophil countAnemiaFeverIncreased total leukocyte countChronic diarrheaPneumoniaHepatomegalyLymphomaLymphadenopathyAutoimmunityAbnormal lymphocyte morphologySevere combined immunodeficiencyDesquamation of skin soon after birthThyroiditisSepsisAplasia/Hypoplasia of the eyebrow

Classification & Codes

Orphanet Code

ORPHA:39041
Omenn syndrome
OrphanetORPHA:39041
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO