optic atrophy
MeSH: D009896ORPHA: 986731 Treatment Available
Overview
disorder characterized by loss of optic nerve fibers. It may be inherited or acquired. Acquired causes include ischemia, optic nerve neuropathy, glaucoma, trauma, radiation, brain tumors, and multiple sclerosis. It leads to vision disturbances
Available Treatments (1)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| idebenone Orphan | oral tablet, 150 mg | EMA Approved | 9 | 21d |
Clinical Presentation
Signs and symptoms associated with optic atrophy, sourced from HPO and Orphanet clinical annotations.
Visual impairmentOptic atrophySensorineural hearing impairmentColor vision defectOphthalmoplegiaSensorimotor neuropathyTemporal optic disc pallorMorning glory anomalyModerately reduced visual acuityPtosisCentral scotomaAtaxiaGait disturbanceMyopathyHypogonadismCataractNystagmusDementiaHallucinationsDiabetes mellitusHypothyroidismSeizureSpasticitySpastic paraplegiaGlobal developmental delayHemiparesisCerebellar atrophyAreflexiaPes cavusMacrocytic anemiaDysphagiaMigraineBasal ganglia calcificationAbnormal periventricular white matter morphologySkeletal muscle atrophyMyalgiaScapular wingingAtrophy/Degeneration affecting the brainstemCorpus callosum atrophyDuane anomalyFeeding difficultiesFatigueWeakness of facial musculatureCognitive impairment
Classification & Codes
MeSH Code
D009896Orphanet Code
ORPHA:98673optic atrophy
| MeSH | D009896 |
| Orphanet | ORPHA:98673 |
| Treatments | 1 drug(s) |
| Symptoms on record | 44 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO