optic atrophy-intellectual disability syndrome

ORPHA: 401777

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with optic atrophy-intellectual disability syndrome, sourced from HPO and Orphanet clinical annotations.

Optic atrophyAutistic behaviorIntellectual disabilitySeizureHypotoniaGlobal developmental delayAbnormal facial shapeHypoplasia of the corpus callosumReduced visual acuityEpicanthusHearing impairmentProtruding earProminent nasal bridgeAnteverted naresStrabismusEsotropiaExotropiaUpslanted palpebral fissureOptic nerve hypoplasiaAmblyopiaCompulsive behaviorsVisual field defectTapered fingerAbsent speechShort nasal bridgeAttention deficit hyperactivity disorderOptic disc hypoplasiaRepetitive compulsive behaviorAbnormal helix morphologyCerebral visual impairmentHypermetropiaMyopiaKeratoconusNystagmusSpasticityDelayed skeletal maturationShort statureDelayed myelinationAbnormal hippocampus morphology

Classification & Codes

Orphanet Code

ORPHA:401777
optic atrophy-intellectual disability syndrome
OrphanetORPHA:401777
Treatments0 drug(s)
Symptoms on record39 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO