osteosclerosis-developmental delay-craniosynostosis syndrome

ORPHA: 178377

Overview

This newly described syndrome is characterized by osteosclerosis, developmental delay and craniosynostosis (see this term)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with osteosclerosis-developmental delay-craniosynostosis syndrome, sourced from HPO and Orphanet clinical annotations.

BrachycephalyMacrocephalyHypertelorismBroad foreheadHigh foreheadHearing impairmentVisual impairmentOptic atrophyCraniosynostosisHeadacheIncreased intracranial pressureThickened calvariaFacial palsyIncreased bone mineral densityMild global developmental delayBroad jaw

Classification & Codes

Orphanet Code

ORPHA:178377
osteosclerosis-developmental delay-craniosynostosis syndrome
OrphanetORPHA:178377
Treatments0 drug(s)
Symptoms on record16 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO