OrphanDrug
OrphanDrug
Pharma Knowledge Base

Palmoplantar keratoderma and spastic paraplegia

MeSH: C536153ORPHA: 2201

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Palmoplantar keratoderma and spastic paraplegia, sourced from HPO and Orphanet clinical annotations.

Palmoplantar keratodermaThickened skinAbnormal fingernail morphologyGait disturbancePes cavusEMG abnormalityPain insensitivityAbnormal toenail morphologyPeripheral neuropathyMuscle flacciditySpasticityHemiplegia

Classification & Codes

MeSH Code

C536153

Orphanet Code

ORPHA:2201
Palmoplantar keratoderma and spastic paraplegia
MeSHC536153
OrphanetORPHA:2201
Treatments0 drug(s)
Symptoms on record12 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO