PANDAS

ICD-10: D89.89MeSH: C537163ORPHA: 66624

Overview

hypothesis that there exists a subset of children with rapid onset of obsessive-compulsive disorder or tic disorders and these symptoms are caused by group A beta-hemolytic streptococcal infections

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with PANDAS, sourced from HPO and Orphanet clinical annotations.

TicsEmotional labilityDepressionIrritabilityPersonality changesChoreaSleep disturbanceDevelopmental regressionAttention deficit hyperactivity disorderObsessive-compulsive traitOppositional defiant disorderImpulsivityAbnormal fear-induced behaviorAgoraphobiaEnuresisAnorexiaPhonophobiaClumsinessArthralgiaRecurrent streptococcus pneumoniae infectionsClaustrophobiaSeparation insecurityEncopresis

Classification & Codes

ICD-10 Code

D89.89

MeSH Code

C537163

Orphanet Code

ORPHA:66624
PANDAS
ICD-10D89.89
MeSHC537163
OrphanetORPHA:66624
Treatments0 drug(s)
Symptoms on record23 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
PANDAS | OrphanDrug