PAPA syndrome
MeSH: C536253ORPHA: 69126
Overview
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome is a rare pleiotropic autoinflammatory disorder of childhood, primarily affecting the joints and skin
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with PAPA syndrome, sourced from HPO and Orphanet clinical annotations.
ProteinuriaAcneArthritisLimitation of joint mobilityFeverLymphadenopathyArthralgiaIncreased circulating immunoglobulin concentrationFatigueIncreased inflammatory responseCrohn's diseaseMyositisType I diabetes mellitusPustuleSkin ulcer
Classification & Codes
MeSH Code
C536253Orphanet Code
ORPHA:69126PAPA syndrome
| MeSH | C536253 |
| Orphanet | ORPHA:69126 |
| Treatments | 0 drug(s) |
| Symptoms on record | 15 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO