Parkes Weber syndrome
ORPHA: 90307
Overview
uncommon congenital vascular malformation (CVM) characterized by the venous malformations, cutaneous capillary malformations, and lymphatic malformations along with arteriovenous malformation.
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Parkes Weber syndrome, sourced from HPO and Orphanet clinical annotations.
Abnormality of the lower limbArteriovenous malformationHigh-output congestive heart failureVascular dilatationVaricose veinsArteriovenous fistulaVascular tortuosityProminent superficial blood vesselsMuscle hypertrophy of the lower extremitiesVenous malformationCapillary malformationErythematous plaqueBounding pulseHemihypertrophy of lower limbPeripheral arteriovenous fistulaUrinary retentionAbnormality of the urinary systemNephrotic syndromeAbnormal bleedingSubarachnoid hemorrhageMyelopathyHeadacheSpinal arteriovenous malformationCerebral arteriovenous malformationAbnormality of the upper limbDistal sensory impairmentBack painSomatic sensory dysfunctionDisseminated intravascular coagulationAbnormal femoral metaphysis morphologyLower limb muscle weaknessHypertrophy of the upper limbLower limb painPainNeck painAbnormal circulating B-type natriuretic peptide concentrationConus terminalis arteriovenous malformationScaling skinChest painAbnormal lymphatic vessel morphologyDural ectasiaSkin ulcerHemangiomatosisParaplegia
Classification & Codes
Orphanet Code
ORPHA:90307Parkes Weber syndrome
| Orphanet | ORPHA:90307 |
| Treatments | 0 drug(s) |
| Symptoms on record | 44 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO