paroxysmal nonkinesigenic dyskinesia 1

ORPHA: 98810

Overview

dystonia characterized by attacks of dystonic or choreathetotic movements precipitated by stress, fatigue, coffee or alcohol intake or menstruation that has material basis in heterozygous mutation in the MR1 gene on chromosome 2q35

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with paroxysmal nonkinesigenic dyskinesia 1, sourced from HPO and Orphanet clinical annotations.

DystoniaParoxysmal dyskinesiaChoreoathetosisChoreaHyperkinetic movementsInvoluntary movementsTrismusTorticollisJoint stiffnessRigidityDyspneaAbnormal speech patternGeneralized muscle weaknessStaring gazeDyskinesia

Classification & Codes

Orphanet Code

ORPHA:98810
paroxysmal nonkinesigenic dyskinesia 1
OrphanetORPHA:98810
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO