Pashayan syndrome

MeSH: C536303ORPHA: 1252

Overview

Blepharonasofacial syndrome is a rare otorhinolaryngological malformation syndrome characterized by a distinctive mask-like facial dysmorphism, lacrimal duct obstruction, extrapyramidal features, digital malformations and intellectual disability

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Pashayan syndrome, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilityAbnormal pinna morphologyMask-like faciesLong philtrumUnderdeveloped nasal alaeWide nasal bridgeWide noseTelecanthusBlepharophimosisLacrimation abnormalityThickened skinTorsion dystoniaRedundant skinFinger syndactylyCleft palateEpicanthusHearing impairmentAbnormal eyelash morphologyIntellectual disabilityHyperreflexiaSparse lateral eyebrowNon-midline cleft of the upper lipInguinal herniaCryptorchidismOptic atrophyAbnormality of the voiceLow posterior hairlineTooth agenesis

Classification & Codes

MeSH Code

C536303

Orphanet Code

ORPHA:1252
Pashayan syndrome
MeSHC536303
OrphanetORPHA:1252
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO