Peters plus syndrome

MeSH: C537617ORPHA: 709

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

syndrome that is characterized by anterior chamber eye anomalies, short limbs with broad distal extremities, characteristic facial features, cleft lip/palate, and variable developmental delay/intellectual disability

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Peters plus syndrome, sourced from HPO and Orphanet clinical annotations.

HypospadiasCleft palateCleft upper lipHydrocephalusHypertelorismPreauricular skin tagWebbed neckMicrocorneaAbnormality of visionCataractUpslanted palpebral fissureNystagmusWidely spaced teethDecreased fetal movementPulmonic stenosisAbnormal cardiac septum morphologyToe syndactylyFrontal bossingShort statureAbnormality of the pulmonary arteryPreauricular pitMicrotia, second degreeFeeding difficulties in infancyPostnatal growth retardationProminent foreheadShort palpebral fissureMulticystic kidney dysplasiaHypoplasia of the uterusInguinal herniaClitoral hypoplasiaUreteral duplicationRenal duplicationHydronephrosisWide mouthMicrocephalyConductive hearing impairmentAnteverted naresVisual impairmentOptic atrophyAnterior hypopituitarismCongenital hypothyroidismSacral dimpleUmbilical herniaPolyhydramniosPatent ductus arteriosusAnal atresiaVentriculomegalyCerebral cortical atrophyShort noseSpina bifida occultaDepressed nasal bridgeWide intermamillary distanceAplasia/Hypoplasia of the corpus callosumRenal hypoplasia/aplasiaRhizomeliaIntestinal fistulaHypoplastic left ventricleBicuspid pulmonary valveAbnormal pulmonary vein morphologyThin upper lip vermilionBrachycephalyLong faceRound faceLong philtrumMicrognathiaShort neckGlaucomaPeters anomalyBrachydactylyIntellectual disabilityGlobal developmental delayIntrauterine growth retardationShort footShort toeShort columellaExaggerated cupid's bowMicromeliaClinodactyly of the 5th fingerAnterior chamber synechiaeCorneal opacityDisproportionate short-limb short statureCryptorchidismPosteriorly rotated ears

Classification & Codes

MeSH Code

C537617

Orphanet Code

ORPHA:709

Peters plus syndrome

MeSH	`C537617`
Orphanet	`ORPHA:709`
Treatments	0 drug(s)
Symptoms on record	83 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO