piebald trait-neurologic defects syndrome

MeSH: C536955ORPHA: 28851 Treatment Available

Overview

human disease

Available Treatments (1)

DrugFormStatusCountriesLead Time
Levodopa/Carbidopa
Oral tablet, various combinations (25/100mg, 25/250mg); Extended-release tabletFDA Approved107d

Clinical Presentation

Signs and symptoms associated with piebald trait-neurologic defects syndrome, sourced from HPO and Orphanet clinical annotations.

Sensorineural hearing impairmentAbnormal eyelash morphologyAbnormal eyebrow morphologyCutaneous photosensitivityPoikilodermaHypopigmented skin patchesHeterochromia iridisIntellectual disabilityAtaxiaAganglionic megacolonHypopigmentation of hairIrregular hyperpigmentationNeoplasm of the skinMacule

Classification & Codes

MeSH Code

C536955

Orphanet Code

ORPHA:2885
piebald trait-neurologic defects syndrome
MeSHC536955
OrphanetORPHA:2885
Treatments1 drug(s)
Symptoms on record14 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO