Pierpont syndrome

MeSH: C566559ORPHA: 487825

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Pierpont syndrome, sourced from HPO and Orphanet clinical annotations.

Everted lower lip vermilionShort neckWidely spaced teethIntellectual disabilityHypotoniaPes planusDeep palmar creaseAbnormal subcutaneous fat tissue distributionWide nasal ridgeNarrow palpebral fissureThin vermilion borderBrachycephalyBroad philtrumHypertelorismSmooth philtrumHigh foreheadPosteriorly rotated earsHearing impairmentStrabismusDeeply set eyeTelecanthusProminent fingertip padsSmall for gestational ageShort toeScoliosisWide intermamillary distanceAtrophy/Degeneration affecting the central nervous systemExcessive wrinkling of palmar skinShort fingerUplifted earlobeLong upper lipPrimary microcephalyAbnormality of the plantar skin of footBrain imaging abnormalityCryptorchidismThin upper lip vermilionMalar flatteningMacrotiaMicrocorneaMicrophthalmiaAbsent speechJoint hypermobilityVentriculomegalyChiari malformationAbnormal cortical gyrationHigh anterior hairlineSevere global developmental delayPendular nystagmus

Classification & Codes

MeSH Code

C566559

Orphanet Code

ORPHA:487825
Pierpont syndrome
MeSHC566559
OrphanetORPHA:487825
Treatments0 drug(s)
Symptoms on record48 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO