pili torti-onychodysplasia syndrome

MeSH: C537399ORPHA: 2890

Overview

Pili torti-onychodysplasia is a form of ectodermal dysplasia characterised by dystrophy of the distal part of the nails and trichodysplasia. It has been described in only one family. Transmission is autosomal recessive.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with pili torti-onychodysplasia syndrome, sourced from HPO and Orphanet clinical annotations.

Ectodermal dysplasiaCleft palateAbnormal pinna morphologyAbsent eyelashesDry skinEczematoid dermatitisPalmoplantar keratodermaAlopeciaAbsent eyebrowAlopecia universalisBrittle hairTrichodysplasiaGeneralized keratosis follicularisCongenital onychodystrophyNail dystrophyKeloidsCutaneous syndactylyConjunctival hyperemiaCleft lipSparse body hair

Classification & Codes

MeSH Code

C537399

Orphanet Code

ORPHA:2890
pili torti-onychodysplasia syndrome
MeSHC537399
OrphanetORPHA:2890
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO