porphyria cutanea tarda

MeSH: D017119ORPHA: 101330

Overview

acute porphyria characterized by painful, blistering skin lesions that develop on sun-exposed skin

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with porphyria cutanea tarda, sourced from HPO and Orphanet clinical annotations.

Abnormal circulating enzyme concentration or activityAbnormal erythrocyte enzyme concentration or activityIncreased circulating ferritin concentrationElevated hepatic iron concentrationDecreased circulating hepcidin concentrationAddictive alcohol useChronic hepatitisSystemic lupus erythematosusStage 5 chronic kidney diseaseDiabetes mellitusHepatic steatosisHematological neoplasmCutaneous photosensitivityAbnormal blistering of the skinFragile skinScaling skinPoor wound healingPainRecurrent bacterial skin infectionsCutaneous abscessHypertrichosisHypopigmentation of the skinHyperpigmentation of the skinHirsutismScarringCorneal scarringEctropionElevated circulating hepatic transaminase concentrationPeriportal fibrosisHepatic lobular inflammationPortal inflammationHepatocellular carcinomaPorphyrinuriaAbnormal circulating porphyrin concentrationIncreased fecal porphyrinIncreased urinary porphobilinogenIncreased circulating iron concentrationViral hepatitis

Classification & Codes

MeSH Code

D017119

Orphanet Code

ORPHA:101330
porphyria cutanea tarda
MeSHD017119
OrphanetORPHA:101330
Treatments0 drug(s)
Symptoms on record38 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO