pretibial dystrophic epidermolysis bullosa
MeSH: C535494ORPHA: 794101 Treatment Available
Overview
Pretibial dystrophic epidermolysis bullosa is a rare subtype of dystrophic epidermolysis bullosa (DEB, see this term) characterized by the development of blisters, erosions, and lichenoid lesions predominantly in the pretibial region
Available Treatments (1)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| Beremagene geperpavec Orphan Cold Chain | Topical gel, 1×10^7 PFU/cm² | FDA Approved | 1 | 14d |
Clinical Presentation
Signs and symptoms associated with pretibial dystrophic epidermolysis bullosa, sourced from HPO and Orphanet clinical annotations.
Abnormal blistering of the skinLocalized skin lesionPretibial blisteringAtypical scarring of skinPruritusFragile skinMiliaAtrophic scarsAbnormal fingernail morphologyAnonychiaPalmoplantar blisteringAbnormal toenail morphologyNail dystrophyKeloidsAbnormality of the eyeCarious teethSmall nailMitten deformityErythematous papuleHyperkeratotic papuleSkin vesicleSkin erosionOral mucosal blisters
Classification & Codes
MeSH Code
C535494Orphanet Code
ORPHA:79410pretibial dystrophic epidermolysis bullosa
| MeSH | C535494 |
| Orphanet | ORPHA:79410 |
| Treatments | 1 drug(s) |
| Symptoms on record | 23 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO