PRKAR1B-related neurodegenerative dementia with intermediate filaments
ORPHA: 412066
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with PRKAR1B-related neurodegenerative dementia with intermediate filaments, sourced from HPO and Orphanet clinical annotations.
DementiaInappropriate behaviorFrontotemporal dementiaMotor deteriorationMemory impairmentAbnormal neuron morphologyShort attention spanAnxietyApathyParkinsonismBradykinesiaPostural instabilityShuffling gaitLanguage impairmentDiffuse cerebral atrophyFallsMuscle stiffnessShort stepped shuffling gaitImpaired visuospatial constructive cognitionInertiaFrontotemporal cerebral atrophy
Classification & Codes
Orphanet Code
ORPHA:412066PRKAR1B-related neurodegenerative dementia with intermediate filaments
| Orphanet | ORPHA:412066 |
| Treatments | 0 drug(s) |
| Symptoms on record | 21 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO