progressive multifocal leukoencephalopathy
MeSH: D007968ORPHA: 217260
Overview
viral disease affecting human brains
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with progressive multifocal leukoencephalopathy, sourced from HPO and Orphanet clinical annotations.
Abnormality of the nervous systemImmunodeficiencyAbnormal cerebrospinal fluid morphologyFunctional motor deficitCNS demyelinationAbnormal CD4+ T cell subset proportionAbnormal oligodendroglia morphologyAbnormal astrocyte morphologyVisual impairmentDysarthriaMental deteriorationGait ataxiaAbnormal speech patternHeadacheSomatic sensory dysfunctionLimb muscle weaknessHemiplegia/hemiparesisDecreased CD8+ T cell proportionWeakness due to upper motor neuron dysfunctionCognitive impairmentNystagmusPersonality changesVisual field defectSeizureParkinsonismVertigoAphasiaHematological neoplasmOculomotor nerve palsySelf-neglectHomonymous hemianopiaDiplopiaMeningitisDysmetriaParesthesia
Classification & Codes
MeSH Code
D007968Orphanet Code
ORPHA:217260progressive multifocal leukoencephalopathy
| MeSH | D007968 |
| Orphanet | ORPHA:217260 |
| Treatments | 0 drug(s) |
| Symptoms on record | 35 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO