progressive osseous heteroplasia
MeSH: C562735ORPHA: 2762
Overview
gene (20q13.2-q13.3), coding for guanine nucleotide-binding proteins. POH can, however, be distinguished clinically by the deep and progressive nature of the heterotopic bone formation.
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with progressive osseous heteroplasia, sourced from HPO and Orphanet clinical annotations.
Abnormality of the parathyroid glandHypermelanotic maculeBrachydactylyLimitation of joint mobilitySubcutaneous noduleBone painOsteoarthritisEctopic calcificationEctopic ossification in muscle tissueMaculeSarcomaPapule
Classification & Codes
MeSH Code
C562735Orphanet Code
ORPHA:2762progressive osseous heteroplasia
| MeSH | C562735 |
| Orphanet | ORPHA:2762 |
| Treatments | 0 drug(s) |
| Symptoms on record | 12 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO