progressive supranuclear palsy-parkinsonism syndrome
MeSH: C537240ORPHA: 240085
Overview
PSP-parkinsonism (PSP-P) is an atypical variant of progressive supranuclear palsy (PSP; see this term), a rare late-onset neurodegenerative disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with progressive supranuclear palsy-parkinsonism syndrome, sourced from HPO and Orphanet clinical annotations.
BradykinesiaAxial muscle stiffnessRigidityTremorAbnormality of eye movementMental deteriorationFallsPostural instabilityRespiratory distressNeuromuscular dysphagiaDystoniaParkinsonism with favorable response to dopaminergic medicationApathyDepressionImpaired visuospatial constructive cognitionVertical supranuclear gaze palsyAbnormal saccadic eye movementsAbnormal speech patternMemory impairment
Classification & Codes
MeSH Code
C537240Orphanet Code
ORPHA:240085progressive supranuclear palsy-parkinsonism syndrome
| MeSH | C537240 |
| Orphanet | ORPHA:240085 |
| Treatments | 0 drug(s) |
| Symptoms on record | 19 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO