prolidase deficiency

MeSH: D056732ORPHA: 742

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with prolidase deficiency, sourced from HPO and Orphanet clinical annotations.

Low anterior hairlineHypertelorismMicrognathiaHearing impairmentAbnormality of the middle earDepressed nasal ridgeVisual impairmentProptosisCarious teethDry skinHyperkeratosisThin skinPalmoplantar keratodermaPruritusCutaneous photosensitivityHirsutismArachnodactylyAbnormal fingernail morphologyIntellectual disabilitySplenomegalyAbnormal facial shapeRecurrent respiratory infectionsWhite forelockGeneralized hirsutismHepatomegalyAbnormality of the immune systemGenu valgumAbnormal hip bone morphologyReduced bone mineral densityDepressed nasal bridgeCrusting erythematous dermatitisBilateral single transverse palmar creasesAbnormal retinal pigmentationAplasia/Hypoplasia of the skinHypoplasia of the zygomatic boneErythemaRecurrent cystitisPapuleSkin ulcer

Classification & Codes

MeSH Code

D056732

Orphanet Code

ORPHA:742
prolidase deficiency
MeSHD056732
OrphanetORPHA:742
Treatments0 drug(s)
Symptoms on record39 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO