Proteus-like syndrome
ORPHA: 2969
Overview
Proteus-like syndrome describes patients who do not meet the diagnostic criteria for Proteus syndrome (see this term) but who share a multitude of characteristic clinical features of the disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Proteus-like syndrome, sourced from HPO and Orphanet clinical annotations.
Polycystic ovariesHydrocephalusMacrocephalyDolichocephalyMandibular prognathiaAnteverted naresDownslanted palpebral fissuresCataractRetinal detachmentMyopiaAbnormal pupil morphologyAbnormality of the parathyroid glandHemangiomaSubcutaneous lipomaHeterochromia iridisLimbal dermoidIntellectual disabilityCommunicating hydrocephalusSplenomegalySkeletal dysplasiaGenu recurvatumVenous insufficiencyIrregular hyperpigmentationShagreen patchThymus hyperplasiaOpen biteEpidermal nevusLower limb asymmetryBronchogenic cystHyperostosisExostoses
Classification & Codes
Orphanet Code
ORPHA:2969Proteus-like syndrome
| Orphanet | ORPHA:2969 |
| Treatments | 0 drug(s) |
| Symptoms on record | 31 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO