pulmonary alveolar proteinosis
MeSH: D011649ORPHA: 747
Overview
lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with pulmonary alveolar proteinosis, sourced from HPO and Orphanet clinical annotations.
Intraalveolar phospholipid accumulationCyanosisClubbingAbnormality of the upper respiratory tractRestrictive ventilatory defectDyspneaFoam cellsAbnormal circulating protein concentrationHypoxemiaIncreased circulating lactate dehydrogenase concentrationAutoimmune antibody positivityDecreased DLCOCoughCrazy paving patternCracklesWeight lossFeverHemoptysisFatigueChest pain
Classification & Codes
MeSH Code
D011649Orphanet Code
ORPHA:747pulmonary alveolar proteinosis
| MeSH | D011649 |
| Orphanet | ORPHA:747 |
| Treatments | 0 drug(s) |
| Symptoms on record | 20 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO